Blast Cellular Mechanics


Impulsive Pressurization of Neuronal Cells

 Based on the assumption that blast-induced overpressure, or high stress impulse, is the main cause of TBI, we investigated the effects of impulsive pressurization on neuronal cell functions. A novel impulsive pressurization apparatus capable of controlling pressure level and duration time has been built using the Kolsky bar set-up. By examining axon shape change, cell apoptosis, and neuronal cell marker (MAP2) gene expression, we expect to reveal the cell/molecular changes under pressurization. More »

Kolsky Bar

Kolsky Bar Blast-mimicking impulsive pressurization is conducted using the Kolsky bar. The direct compression Kolsky bar works by storing strain energy and then releasing it as a near square wave of strain. More »

Overview

 Blast Cellular Mechanics focuses on identifying the mechanical properties of neuronal brain cells, especially in blast loading conditions. This research is being done by using a Kolsky bar set-up to perform controlled pressure bursts then analyzing cell deformation.