Hi, welcome to my page!
I am a PhD candidate in the Chemical and Biomolecular Engineering department at UNL. I have been a part of this department since 2012, first earning my BS in 2017 and then my BS in 2019.
I have been a member of the Systems and Synthetic Biology laboratory, since August, 2017. My main projects revolve around creating metabolic models of different complexity to help answer questions that are too difficult to be answered experimentally. The models can be used to (i) engineer new strains of bacteria that produce an industrially relevant product, (ii) generate hypothesis on the fundamental rules governing the way cells grow, (iii) or predicting the presence of phenomena to explain a set of seemingly unrelated observations. I am also lucky since some of my projects have an experimental component to them, which means that I can collaborate with other members in the lab to test the predictions made by the models.
My current projects involve
i) Development and analysis of a genome-scale metabolic model for the analysis of Rhodopseudomonas palustris;
ii) Development and analysis of a kinetic model of sphingolipid biosynthesis in Arabidopsis thaliana;
iii) Metabolic engineering of Rhodopseudomonas palustris for bioproduction of bioplastic.
Outside of work, I like to spend my time swimming, running, reading, or hanging out with family and friends.
Here is a list of my publications:
- Alsiyabi, A., Immethun, C.M. & Saha, R. Modeling the Interplay between Photosynthesis, CO2 Fixation, and the Quinone Pool in a Purple Non-Sulfur Bacterium. Sci Rep 9, 12638 (2019).
- Islam, M. M., Al-Siyabi, A., Obata, T., and Saha, R., "Dissecting metabolic flux in C4 plants: experimental and theoretical approaches", Phytochemistry Reviews, https://doi.org/10.1007/s11101-018-9579-8 (2018).