• Lab Web Site
• Society of Biological Engineering (SBE)
• International Metabolic Engineering Society (MES)
• American Chemical Society (ACS)
• American Society of Plant Biologists (ASPB)
- Ph.D., Chemical Engineering, The Pennsylvania State University (2014)
- M.S., Chemical Engineering, The Pennsylvania State University (2011)
- B.S., Chemical Engineering, Bangladesh University of Engineering and Technology (2005)
- One PhD Student starting from the Fall 2017.
- One MS Student starting from the Fall 2017.
- Reconstruction and analysis of genome-scale and community models
- Systems-level analysis of ‘omics’ data
- Development of genetic toolkit and engineering metabolic pathways
- Redesign photosynthetic apparatus and carbon fixing mechanism
Dr. Rajib Saha is a new assistant professor in the Department of Chemical & Bimolecular Engineering at UNL. Prior to his appointment at UNL, he worked as a post-doctoral research associate in the Himadri Pakrasi Lab in Biology department at Washington University in St. Louis. He graduated with his PhD and MS in Chemical Engineering from the Costas Maranas Lab at The Pennsylvania State University in 2014 and 2011, respectively. He got his Bachelor in Chemical Engineering from Bangladesh University of Engineering and Technology with the top position in his graduating class.
Throughout his multidisciplinary graduate research career, he has developed metabolic network models for photosynthetic organisms and subsequently utilized those for studying their physiology and also for metabolic engineering applications. His recent postdoctoral research includes study of light/dark behavior and development of efficient and tunable gene expression control system of a model cyanobacterial strain. His research interests include reconstruction and analysis of genome-scale and community models, systems-level analysis of ‘omics’ data, development of genetic toolkit and engineering metabolic pathways, and redesign photosynthetic apparatus and carbon fixing mechanism.
2016 - Assistant Professor
Chemical & Biomolecular Engineering
University of Nebraska-Lincoln
2014 - 2016 Postdoctoral Research Fellow
Department of Biology, Washington University in St. Louis
Advisor: Dr. Himadri B. Pakrasi
2009-2014 Graduate Research Assistant
Department of Chemical Engineering, The Pennsylvania State University
Advisor: Dr. Costas Maranas
2005-2009 Research Scholar
Department of Chemical and Biomolecular Engineering, National University of Singapore
(* indicates authors with equal contribution.)
- Saha, R.*, Liu, D.*, O'Connor, A.G., Liberton, M., Yu, J., Bhattacharyya, M., Balassy, A. , Zhang, F., Moon, T.S., Maranas, C.D. and Pakrasi, H.B. (2016), “Diurnal Regulation of Cellular Processes in the Cyanobacterium Synechocystis sp. PCC 6803: Insights from Transcriptomic, Fluxomic and Physiological Analyses”, mBio, 7(3), e00464-16.
- Liberton, M.*, Saha, R.*, Jacobs, J. M.*, Nguyen, A.Y., Chrisler, W.B., Gritsenko, M.A., Smith, R.D., Koppenaal, D.W. and Pakrasi, H.B. (2016), “Proteomics analysis of isolated plasma membrane and thylakoid membrane from Synechocystis sp. PCC 6803”, Molecular and Cellular Proteomics, 15(6), 2021-2032.
- Berla, B.M., Saha, R., Maranas, C.D. and Pakrasi, H.B. (2015), “Cyanobacterial Alkanes Modulate Photosynthetic Cyclic Electron Flow to Assist Growth under Cold Stress”, Nature Scientific Reports, 5, doi: 10.1038/srep14894.
- Simons, M.*, Saha, R.*, Amiour, N., Kumar, A., Guillard, L, Clément, G., Miquel, M., Zheni, L., Mouille, G., Hirel, B. and Costas D. Maranas (2014), “Assessing the Metabolic Impact of Nitrogen Availability using a Compartmentalized Maize Leaf Genome-Scale Model”, Plant Physiology, 166: 1659-1674.
- Simons, M, Saha, R., Guillard, L., Clement, G., Armengaud, P., Canas, R, Maranas, C.D., Lea, P.J. and B. Hirel (2014), “Nitrogen-use efficiency in maize (Zea mays L.): from ‘omics’studies to metabolic modelling”, Journal of Experimental Botany, doi: 10.1093/jxb/eru227.
- Saha, R, Liu, D., Hoynes-O’Connor, A.G., Liberton, M., Yu, J., Bhattacharyya, M., Balassy, A., Moon, T.S., Maranas, C.D., Pakrasi, H.B., “Synechocystis Sp. PCC 6803: Light Plus Endogenous Regulation Governing Gene Expression Patterns in the Diurnal Cycle”, AIChE annual meeting, Salt Lake City, UT, Nov 8-13, 2015.
- Saha, R., Berla, B.M., Pakrasi, H.B. and Maranas, C.D., “Computations-driven optimization of alkane production in Synechocystis sp. PCC 6803”, AIChE annual meeting, Atlanta, GA, Nov 16-21, 2014.
- Saha, R., Simons, M., Kumar, A., Guillard, L., Hirel, B and Maranas, C.D., “Towards multi-tissue type metabolic modeling of maize”, AIChE annual meeting, San Francisco, CA, Nov 3-8, 2013.
- Saha, R., Berla, B.M., Mueller, T.J., Welkie, D.J., Sherman, L., Pakrasi, H.B. and Maranas, C.D., “Comparative genome-scale modeling of the metabolic potential of cyanobacteria Cyanothece sp. ATCC 51142 and Synechocystis sp. PCC6803”, 11th workshop on cyanobacteria, St. Louis, MO, Aug 7-11, 2013.