The BPDF has performed process development of biologics, specializing in peptides and recombinant proteins, from microbial systems for over 19 years and have produced GMP materials for over 13 years, producing over 50 products including vaccines, bio therapeutics, chemokines, and agricultural/industrial enzymes. Current clients include government, industry, and philanthropic organizations. Most recently, the BPDF developed and scaled-up a process for GMP production of 5P12-RANTES, a microbicide effective in preventing transmission of HIV in vitro. These and other projects involved process development, analytical methods development and qualification, process scale up, GMP manufacturing, and stability studies.