Translational Mechanobiology Lab



  • Collaborator Dr. Ranil de Silva implants a shear-modifying stent into the left anterior descending coronary artery of a hypercholesterolemic pig (Pedrigi et al., Circulation, 2015). Collaborator Dr. Ranil de Silva implants a shear-modifying stent into the left anterior descending coronary artery of a hypercholesterolemic pig (Pedrigi et al., Circulation, 2015).
  • Micro-CT images of a mouse carotid artery instrumented with a flow-modifying cuff (yellow arrow) and corresponding map of wall shear stress (WSS) obtained from CFD (Pedrigi et al., R Soc Open Sci, 2016). Micro-CT images of a mouse carotid artery instrumented with a flow-modifying cuff (yellow arrow) and corresponding map of wall shear stress (WSS) obtained from CFD (Pedrigi et al., R Soc Open Sci, 2016).
  • Comparison of the patterns of metrics of disturbed blood flow (LSI and tSS) over time to atherosclerotic plaque type at the final study time point within a hypercholesterolemic pig (Pedrigi et al., Circulation, 2015). Comparison of the patterns of metrics of disturbed blood flow (LSI and tSS) over time to atherosclerotic plaque type at the final study time point within a hypercholesterolemic pig (Pedrigi et al., Circulation, 2015).
  • Image of a human donor eye lens capsule in situ with implanted intraocular lens (IOL), from which annular specimens were excised for uniaxial mechanical behavior testing (Pedrigi et al., Exp Eye Res, 2009). Image of a human donor eye lens capsule in situ with implanted intraocular lens (IOL), from which annular specimens were excised for uniaxial mechanical behavior testing (Pedrigi et al., Exp Eye Res, 2009).
  • Fluorescent microscopy images of endothelial cells stained for DAPI and NF-κB after exposure to normal, reduced, and multidirectional stretch (Pedrigi et al., Ann Biomed Eng, 2017). Fluorescent microscopy images of endothelial cells stained for DAPI and NF-κB after exposure to normal, reduced, and multidirectional stretch (Pedrigi et al., Ann Biomed Eng, 2017).