Project explores ultrasound therapy to promote cardiovascular health

March 30, 2020

Ryan Pedrigi, assistant professor of mechanical and materials engineering at the University of Nebraska–Lincoln, will use a five-year, $543,000 award from the National Science Foundation’s Faculty Early Career Development Program to lay the groundwork for a targeted, noninvasive treatment for atherosclerosis.
Ryan Pedrigi, assistant professor of mechanical and materials engineering at the University of Nebraska–Lincoln, will use a five-year, $543,000 award from the National Science Foundation’s Faculty Early Career Development Program to lay the groundwork for a targeted, noninvasive treatment for atherosclerosis.
Craig Chandler / University Communication and Marketing

Cardiovascular disease is the leading cause of death in the United States, killing approximately 647,000 Americans each year. It’s also expensive, accounting for more in health care expenditures — $190 billion annually — than any other diagnostic group.

Atherosclerosis, or plaque buildup in the inner lining of arteries, is a primary driver of cardiovascular disease. There are two main treatment options. Statins, prescription drugs that lower levels of the blood cholesterol responsible for plaque formation, can reduce the risk of heart attack and stroke, but they are not targeted to the diseased artery. Stents — tiny tubes that keep blocked arteries open — are targeted, but their invasive nature poses serious risks to the patient.

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