The BPDF offers a variety of analytical services, including method development, transfer, verification, and qualification with expertise in protein/peptide characterization and identification. Analytical testing services are provided for a variety of standard test methods using both in-house and compendial test methods.
The BPDF also provides custom method development and method qualification services for characterization and identification of proteins/peptides at various stages of product development. We also work with clients to develop and execute real-time and accelerated stability testing programs, including forced degradation and freeze-thaw studies.
Instruments and Equipment
- Waters Alliance® and modular HPLC systems with UV, photodiode array, and refractive index detectors
- Waters Acquity® UPLC with photodiode array detector
- Waters Empower® 3 chromatography software
- Molecular Devices SectraMax® M2 microplate reader with scanning UV and fluorescence detection
- YSI 3200 Conductivity Instrument
- Thermo Fisher EvolutionTM 300 UV Spectrophotometer
- GE SieversTM 900 Total Organic Carbon Analyzer
- Charles River Labs Endosafe® Nexgen-MCSTM endotoxin analyzer
- Bio-Rad GS-800TM Calibrated Densitometer
- FungilabViscoleadTM Pro rotational viscometer
- Thermo Fisher XCellSureLock® Mini-Cell and NuPage® Novex® gel electrophoresis system
- Stability chambers for studies at ≤-70°C, -20°C, 2-8°C and 25°C/60%