The GMP facility can accommodate both recombinant bacteria and yeast expression systems at the 150 L-scale (working volume).
The facility is fully equipped with all the necessary downstream processing equipment to purify either intracellular or secreted proteins.
![First Floor Facility Floor Plan](images/bpdf/cGMP_layout800.jpg)
The new GMP pilot plant has the following GMP utilities: a Pure Steam Generator with a Water For Injection (WFI) condenser, 1000 gal WFI storage tank, a distribution system for both ambient and hot WFI throughout the pilot plant with drops in all processing suites, and a dedicated process chilled water system.
The pilot plant also has an uninterruptible power supply (UPS) for all critical processing equipment supported by an emergency back-up generator.
Being a stand-alone facility, the BPDF has the ability to make and test all buffers and solutions needed for GMP production.